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Registros recuperados: 191
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Effects of a Sarcocystis gigantea Extract (SGE) on the Replication of Human Immunodeficiency Virus (HIV) OAK
Drösigk, U.; Tietz, H. J.; Pözsch, F.; Scholz, D.; Hiepe, T. H..
Palavras-chave: Sarcocystis gigantea; Lectin; Immunomodulation; Human Immunodeficiency Virus; HIV.
Ano: 1995 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/235
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Human group C rotavirus in children with diarrhea in the Federal District, Brazil BJMBR
Teixeira,J.M.S.; Camara,G.N.N.L.; Pimentel,P.F.V.; Ferreira,M.N.R.; Ferreira,M.S.R.; Alfieri,A.A.; Gentsch,J.R.; Leite,J.P.G..
Group C rotaviruses are fastidious in their in vitro cell culture requirements. Recent serosurveys indicate that antibody to group C rotavirus is present in 3-45% of the human population in certain geographic locations, suggesting that rotavirus group C infection is more prevalent than previously believed and that the low rate of detection of these agents is probably due to the lack of sensitive diagnostic assays. From March to December 1994, 406 fecal specimens were collected from children under five years of age who were outpatients at the emergency services of nine public hospitals in Brasília, Federal District, Brazil. In addition to the samples from children, one public outpatient unit requested virological investigation of a stool sample from an...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Group C rotavirus; Diarrhea; HIV; RT-PCR; Probe hybridization.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001100005
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Two variants of HIV-1 B serotype are transmitted heterosexually in São Paulo, Brazil BJMBR
Casseb,J.; Hong,M.A.; Gonsalez,C.; Brígido,L.F.; Duarte,A.J.S.; Michael-Hendry,R..
HIV-1 variability may have an important impact on transmission and pathogenicity. Better characterization of the HIV epidemic in Brazil is necessary for the development of vaccine trials in this country. We analyzed sera from 108 HIV-1-infected volunteers from São Paulo City to determine serotype and reactivity for V3 motifs of HIV in this population, and the relationship to transmission mode. We concluded that the HIV-1 B serotype is frequent among heterosexually infected women, even in the absence of anal sex, and that two major V3 motifs, GPGR and GWGR, had similar prevalence among women (48% and 52%, respectively) and men (56% and 44%, respectively). We also observed an equal distribution of these strains regardless of their CD4+ T cell counts,...
Tipo: Info:eu-repo/semantics/other Palavras-chave: HIV; Serotyping; Gp 120 V3 loop; Synthetic peptides; Sexual transmission.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001000002
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The Mathematical Biology of Human Infections Ecology and Society
Nowak, Martin A; Institute for Advanced Study; nowak@ias.edu.
Humans are constant victims of infectious diseases. Biomedical research during this century has led to important insights into the molecular details of immune defense. Yet, many questions relating to disease require a quantitative understanding of the complex systems that arise from the nonlinear interactions between populations of immune cells and infectious agents. Exploration of such questions has lead to a newly emerging field of mathematical biology describing the spread of infectious agents both within and between infected individuals. This essay will discuss simple and complex models of evolution, and the propagation of virus and prion infections. Such models provide new perspectives for our understanding of infectious disease and provide guidelines...
Tipo: Peer-Reviewed Reports Palavras-chave: CTL response; HIV; Antivirals; Epidemiology; Immune response; Infectious diseases; Mathematical biology; Models of evolution; Prions; Resistance; Treatment; Viruses.
Ano: 1999
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Successful prevention of HIV transmission from mother to infant in Brazil using a multidisciplinary team approach BJID
Nogueira,Susie A.; Abreu,Thalita; Oliveira,Ricardo; Araújo,Lúcia; Costa,Tomaz; Andrade,Miriam; Psic,M. Fátima Garcia; Machado,Elizabeth; Rodrigues,Káris; Mercadante,Elizabeth Regina; Fernandes,Iraína; Sapia,M. Conceição; Lambert,John S..
OBJECTIVES: To determine the HIV vertical transmission rate (VTR) and associated risk factors by use of zidovudine and infant care education in Brazil. METHODS: Since 1995, a prospective cohort of HIV infected pregnant women has been followed at the Federal University of Rio de Janeiro. A multidisciplinary team was established to implement the best available strategy to prevent maternal-infant HIV transmission. Patients with AIDS or low CD4 and high viral load received anti-retroviral drugs in addition to zidovudine. Children were considered infected if they had 2 positive PCR-RNA tests between 1 and 4 months of age, or were HIV antibody positive after 18 months. Education regarding infant treatment and use of formula instead of breast feeding was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Brazil; HIV; Prevention; Perinatal transmission; Zidovudine.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000200006
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Detection of mycobacteria in the bloodstream of patients with Acquired Immunodeficiency Syndrome in a University Hospital in Brazil BJID
Oplustil,Carmen Paz; Leite,Olavo H.M.; Oliveira,Marilia S.; Sinto,Sumiko I.; Uip,David E.; Boulos,Marcos; Mendes,Caio F..
This study was done to determine the occurrence of mycobacteria in the bloodstreams of patients with fever and advanced AIDS in a Brazilian hospital. We also verified the capability of an automated method for recovering these bacteria. During a period of 19 months, 254 patients with AIDS were evaluated. Blood cultures were generally submitted in pairs and drawn separately. Blood cultures were processed by the BACTEC 460TB System (Becton Dickinson Microbiology Systems, Sparks, MD), using the Bactec 13A media (Becton Dickinson Microbiology Systems, Sparks, MD). Of the 530 vials submitted, 77 (14.5%) from 41 (16%) patients were positive. Mycobacterium avium complex was recovered from 45 (58.4%) of the 77 positive vials, corresponding to 22 (53.6%) patients...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mycobacterial infection; HIV; Automated diagnosis; AIDS.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000500003
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Lipid and acute-phase protein alterations in HIV-1 infected patients in the early stages of infection: correlation with CD4+ lymphocytes BJID
Treitinger,Arício; Spada,Celso; Silva,Laura Maria D. da; Hermes,Elizabeth Martins; Amaral,Jorge Antônio; Abdalla,Dulcineia Saes Parra.
Lipid and acute-phase protein alterations have been described in various infection diseases, and they have been recorded during the early stages of HIV infection. Lipid and acute-phase protein profiles also have been correlated with cellular immunological abnormalities. To document these correlations during HIV infection, we studied 75 HIV-infected patients and 26 HIV-negative controls. Patients were classified according to the criteria proposed by the Walter Reed Army Institute: as WR-1 (CD4 lymphocytes, 1154 ± 268/mm³), WR-2 (CD4, 793 ± 348/mm³) and WR3/4 (CD4, 287±75 mm³). Triglycerides, total cholesterol and HDL-cholesterol concentrations were measured by enzymatic methods. Immunoglobulins (IgA and IgG) and acute-phase proteins (haptoglobin, a1-acid...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; CD4+; Triglycerides; IgA; A1-acid glycoprotein; Haptoglobin.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400005
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Comparison of the quantitative competitive and semiquantitative RT-PCR methods for the determination of interferon-gamma mRNA levels in AIDS-free HIV-infected individuals BJMBR
Barabás,É.; Nagy,K.; Várkonyi,V.; Horváth,A..
IFN-gamma mRNA expression was evaluated in nonstimulated peripheral blood mononuclear cells (PBMC) of HIV-infected and seronegative individuals using quantitative competitive and semiquantitative RT-PCR and the sensitivity of these methods was compared. A significant correlation was found between quantitative competitive and semiquantitative RT-PCR in samples of both HIV-seronegative (P = 0.004) and HIV-infected individuals (P = 0.0004). PBMC from HIV-infected individuals presented a remarkable increase of IFN-gamma mRNA expression, as determined by both types of RT-PCR methods. Semiquantitative RT-PCR even without an internal standard is also acceptable for measuring cytokine mRNA expression, but less reliable if small amounts are quantified. Moreover, we...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Quantitative competitive RT-PCR; Semiquantitative RT-PCR; IFN-gamma mRNA; HIV.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000006
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Predictors of undetectable plasma viral load in HIV-positive adults receiving antiretroviral therapy in Southern Brazil BJID
Silveira,Marysabel Pinto Telis; Draschler,Maria de Lourdes; Leite,José Carlos de Carvalho; Pinheiro,Cezar Arthur Tavares; Silveira,Vera Lúcia da.
Factors associated with undetectable viral load (<80 copies/ml) were investigated among non-pregnant adults in antiretroviral treatment in a specialized service for HIV/AIDS in Southern Brazil. Use of antiretrovirals was investigated in two interviews (one month interval). Clinical data were collected from the clinical records; viral load previous to adherence measurement was defined the viral load previous to the first interview; the final viral load, the viral load subsequent to the second interview (interval between measures approximately 6 months). Undetectable final viral load occurred in 48% of the patients and was positively associated with levels of treatment adherence (p<0.001), being 19% for less than 60% of adherence and about 60% for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; Antiretroviral therapy; Adherence; Viral load; Predictors; Risk factors.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000400003
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HIV prevalence among blood donors in a blood bank in Curitiba (Brazil) BJID
Andrade Neto,José Luiz; Pintarelli,Vitor Last; Felchner,Paulo Cesar Zimmermann; Morais,Rodrigo Leite de; Nishimoto,Fabíola Lie.
There still is no cure for the acquired immunodeficiency syndrome (AIDS). Its etiologic agent is the human immunodeficiency virus (HIV), and transmission occurs through sexual relationships, contacts with blood, and vertically (mother to child). In this study, we sought to determine the prevalence of HIV among blood donors at a blood bank in Curitiba. We studied 213,666 blood donations made from March 1, 1992, to April 25, 1999. Each potential blood donor first answered a questionnaire, submitted to a clinical examination, and filled out a self-exclusion card. Blood was collected and analyzed only from the candidates approved by the first two criteria. Two tests were used to detect HIV: ELISA for screening, and Western-Blot for confirmation. The results...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AIDS; Blood donor; HIV.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000100003
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Bilateral peripheral facial palsy secondary to lymphoma in a patient with HIV/AIDS: a case report and literature review BJID
Sasaki,Maria das Graças; Leite,Patrícia G. B.; Leite,Andréa G. B.; Almeida,Sérgio Monteiro de.
Neurological complications represent one of the most important causes of morbidity and mortality in patients with HIV/AIDS. However, peripheral neuropathy comprises only 5% to 20% of the total neurological complications and facial nerve palsy, especially when it is bilateral, is a less common manifestation. Peripheral facial palsy has been considered as a possible neurological complication of the early stage of HIV infection but the number of reported cases in the literature is limited. Histological findings of nervous tissue in peripheral facial palsy at an early stage of HIV infection include a degenerative and not suppurative inflammatory process, but its etiology remains obscure. Peripheral facial palsy in the late stage of HIV infection is...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; Facial palsy; Lymphoma.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000100008
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Factors associated with adherence to antiretroviral therapy in HIV/AIDS patients: a cross-sectional study in Southern Brazil BJMBR
Pinheiro,C.A.T.; de-Carvalho-Leite,J.C.; Drachler,M.L.; Silveira,V.L..
A cross-sectional study was conducted on HIV-infected adults being treated with antiretroviral drugs at a reference service in Southern Brazil. Participants answered a sociodemographic questionnaire and were tested by scales assessing sociocognitive variables. Adherence to treatment was assessed by a self-report inventory developed for the study. Clinical information was obtained from the patients' records. Significance tests were conducted using univariate logistic regressions followed by multivariate logistic regression analysis. A total of 195 patients participated in the study and 56.9% of them reported > or = 95% adherence on the previous two days. In univariate analysis, the odds of adherence increased with self-efficacy (a person's conviction...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adherence; Antiretroviral therapy; Self-efficacy; HIV; AIDS.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001000010
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Evidence of Returns to Schooling in Africa from Household Surveys: Monitoring and Restructuring the Market for Education AgEcon
Schultz, T. Paul.
Wage-differentials by education of men and women are examined from African household surveys to suggest private wage returns to schooling. It is commonly asserted that returns are highest at primary school levels and decrease at secondary and postsecondary levels, whereas private returns in six African countries are today highest at the secondary and post secondary levels, and rates are similar for women as for men. The large public subsidies for postsecondary education in Africa, therefore, are not needed to motivate students to enroll, and those who have in the past enrolled in these levels of education are disproportionately from the better-educated families. Higher education in Africa could be more efficient and more equitably distributed if the...
Tipo: Working or Discussion Paper Palavras-chave: Africa; Wage returns to schooling; Inequality; HIV; AIDS; Labor and Human Capital; 015; 055; J31; J24.
Ano: 2003 URL: http://purl.umn.edu/28481
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Functional assesment of patients with AIDS disease BJID
Zonta,Marise Bueno; Almeida,Sérgio Monteiro de; Carvalho,Mirian T. M. de; Werneck,Lineu César.
We documented the types and degree of functional disability in 74 patients with AIDS at the Hospital de Clínicas of the Federal University of Paraná, Brazil. Few of these patients are referred for rehabilitation services and there is only a limited team approach in their care. We found that 91% of the patients had some degree of functional impairment; in 81% the complaint was weakness and in 47% it was neurological involvement. According to the Barthel Index, 79% were considered functionally independent, 14% partially dependent and 7% dependent. For most of them, independence requires effort and their quality of life is reduced. Severe disability was rather unusual, while mild or moderate disability levels were not. The functional physical disability found...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; AIDS; Rehabilitation; Functional disability; Health status; Neurological manifestation.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500004
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Evaluation of techniques for the diagnosis of Strongyloides stercoralis in human immunodeficiency virus (HIV) positive and HIV negative individuals in the city of Itajaí, Brazil BJID
Blatt,Jucelene Marchi; Cantos,Geny Aparecida.
Human immunodeficiency virus (HIV) and intestinal parasites are common in Brazil. Previous studies have shown that infection with Strongyloides stercoralis is frequently associated with HIV infection. Strongyloidiasis is difficult to diagnosis and stool examination with conventional techniques fails to detect the helminth larvae. We made a prospective study, to test the efficacy of the agar plate technique to detect S. stercoralis in 211 HIV-positive patients and 213 HIV-negative patients in the city of Itajaí, Brazil, between September 2001 and June 2002. The feces samples of these patients were processed and analyzed according to the following methods: Lutz, formalin ethyl acetate, Baermann, Harada-Mori and agar plate culture. HIV-positive patients were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Agar plate culture; HIV; Strongyloides stercoralis.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000600008
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AIDS-associated diarrhea and wasting in northeast Brazil is associated with subtherapeutic plasma levels of antiretroviral medications and with both bovine and human subtypes of Cryptosporidium parvum BJID
Brantley,Richard K.; Williams,K. Robert; Silva,Terezinha M.J.; Sistrom,Maria; Thielman,Nathan M.; Ward,Honorine; Lima,Aldo A. M.; Guerrant,Richard L..
Advanced HIV infection is frequently complicated by diarrhea, disruption of bowel structure and function, and malnutrition. Resulting malabsorption of or pharmacokinetic changes in antiretroviral agents might lead to subtherapeutic drug dosing and treatment failure in individual patients, and could require dose adjustment and/or dietary supplements during periods of diarrheal illness. We determined the plasma levels of antiretroviral medications in patients that had already been started on medication by their physicians in an urban infectious diseases hospital in northeast Brazil. We also obtained blood samples from patients hospitalized for diarrhea or AIDS-associated wasting, and we found reduced stavudine and didanosine levels in comparison with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; Malabsorption; DdI; D4T; Pharmacokinetics.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000100003
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Looking for exceptions on knowledge rules induced from HIV cleavage data set Genet. Mol. Biol.
Prati,Ronaldo Cristiano; Monard,Maria Carolina; Carvalho,André C. P. L. F. de.
The aim of data mining is to find useful knowledge inout of databases. In order to extract such knowledge, several methods can be used, among them machine learning (ML) algorithms. In this work we focus on ML algorithms that express the extracted knowledge in a symbolic form, such as rules. This representation may allow us to ''explain'' the data. Rule learning algorithms are mainly designed to induce classification rules that can predict new cases with high accuracy. However, these sorts of rules generally express common sense knowledge, resulting in many interesting and useful rules not being discovered. Furthermore, the domain independent biases, especially those related to the language used to express the induced knowledge, could induce rules that are...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Data mining; Exceptions; HIV; Protease.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400027
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Análise da Mortalidade de Adultos Nos Agregados Familiares Rurais em Moçambique e Implicações para Políticas. AgEcon
Mather, David; de Marrule, Higino Francisco; Donovan, Cynthia; Weber, Michael T.; Alage, Albertina.
Resultados de pesquisa do Departmento de Análise de Políticas, MADER, Direcção de Economia
Tipo: Report Palavras-chave: Food security; Food policy; Mozambique; AIDS; HIV; Health Economics and Policy; Q18.
Ano: 2004 URL: http://purl.umn.edu/55240
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Analysis of Adult Mortality Within Rural Households in Mozambique and Implication For Policy AgEcon
Mather, David; de Marrule, Higino Francisco; Donovan, Cynthia; Weber, Michael T.; Alage, Albertina.
Research results from the Department of Policy Analysis, MADER, Directorate of Economics
Tipo: Report Palavras-chave: Food security; Food policy; Mozambique; AIDS; HIV; Health Economics and Policy; Q18.
Ano: 2004 URL: http://purl.umn.edu/55239
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Transfusion risk for hepatitis B, hepatitis C and HIV in the state of Santa Catarina, Brazil, 1991-2001 BJID
Kupek,Emil.
We examined the time trend of residual risk of transfusing blood contaminated with HIV, hepatitis B and hepatitis C, in the largest blood bank of the state of Santa Catarina, Brazil, 1991-2001. The HIV risk was reduced approximately 10 times during the decade of 1990, to 1:48777, but then increased significantly by the end of 2001. A similar time trend was observed for hepatitis B and hepatitis C, although the increase was not significant in this case. Even during the period of lowest risk, the estimates were considerably higher than in developed countries.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Blood transfusion; HIV; Hepatitis B; Hepatitis C.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000300007
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